Phosphorylation by Casein Kinase 2 Facilitates rRNA Gene Transcription by Promoting Dissociation of TIF-IA from Elongating RNA Polymerase I

The protein kinase casein kinase 2 (CK2) phosphorylates different components of the RNA polymerase I (Pol I) transcription machinery and exerts a positive effect on rRNA gene (rDNA) transcription. Here we show that CK2 phosphorylates the transcription initiation factor TIF-IA at serines 170 and 172...

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Hlavní autoři: Bierhoff, Holger, Dundr, Miroslav, Michels, Annemieke A., Grummt, Ingrid
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519707/
https://ncbi.nlm.nih.gov/pubmed/18559419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00492-08
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