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Structural evolution of p53, p63, and p73: Implication for heterotetramer formation

Oligomerization of members of the p53 family of transcription factors (p53, p63, and p73) is essential for their distinct functions in cell-cycle control and development. To elucidate the molecular basis for tetramer formation of the various family members, we solved the crystal structure of the hum...

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Main Authors: Joerger, Andreas C., Rajagopalan, Sridharan, Natan, Eviatar, Veprintsev, Dmitry B., Robinson, Carol V., Fersht, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764906/
https://ncbi.nlm.nih.gov/pubmed/19815500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905867106
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