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Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice
Despite 2 decades of research, no clear function for annexin A1 (AnxA1) has been established. Using AnxA1-KO mice, we show that tumor growth and metastasis are significantly decreased, whereas rodent survival and tumor necrosis are greatly increased when tumors grow in AnxA1-KO mice. Systems analysi...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764877/ https://ncbi.nlm.nih.gov/pubmed/19805119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901324106 |
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