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Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice

Despite 2 decades of research, no clear function for annexin A1 (AnxA1) has been established. Using AnxA1-KO mice, we show that tumor growth and metastasis are significantly decreased, whereas rodent survival and tumor necrosis are greatly increased when tumors grow in AnxA1-KO mice. Systems analysi...

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Detalhes bibliográficos
Main Authors: Yi, Ming, Schnitzer, Jan E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764877/
https://ncbi.nlm.nih.gov/pubmed/19805119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901324106
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