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Exploring Molecular Mechanisms of Ligand Recognition by Opioid Receptors with Metadynamics
Opioid receptors are G protein-coupled receptors (GPCRs) of utmost significance in the development of potent analgesic drugs for the treatment of severe pain. An accurate evaluation at the molecular level of the ligand binding pathways into these receptors may play a key role in the design of new mo...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764813/ https://ncbi.nlm.nih.gov/pubmed/19785461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901494n |
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