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Synthesis, Characterization and Anti-Melanoma Activity of Tetra-O-substituted Analogs of Nordihydroguaiaretic Acid
Synthesis of seven semi-synthetic analogs of NDGA is described. An approach to NDGA derivitization is described in which the ortho-phenolic groups are tethered together by one atom, forming a 5-membered heterocyclic ring. The analogs were evaluated for cytotoxicity in four cancer cell lines and comp...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764744/ https://ncbi.nlm.nih.gov/pubmed/19615898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.06.063 |
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