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Synthesis and application of 2′-fluoro substituted cap analogs
Design, synthesis and biological evaluation of 2′-fluoro substituted cap analogs, i.e. m(7, 2′F) G[5′]ppp[5′]G and m(7, 2′F) G[5′]ppp[5′]m(7)G are described. Structures were confirmed by ¹H, (31)P, (19)F NMR and MS data. The effects of the 2′-fluoro substituted moiety from the normal and N(7) double...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151044/ https://ncbi.nlm.nih.gov/pubmed/17728131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.08.029 |
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