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Multiple B-vitamin inadequacy amplifies alterations induced by folate depletion in p53 expression and its downstream effector MDM2

Folate is required for biological methylation and nucleotide synthesis, aberrations of which are thought to be the mechanisms that enhance colorectal carcinogenesis produced by folate inadequacy. These functions of folate also depend on the availability of other B-vitamins that participate in “one-c...

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Détails bibliographiques
Auteurs principaux: Liu, Zhenhua, Choi, Sang-Woon, Crott, Jimmy W., Smith, Donald E., Mason, Joel B.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764718/
https://ncbi.nlm.nih.gov/pubmed/18498130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23599
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