Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations14

BACKGROUND: Folate is an essential nutrient that supports nucleotide synthesis and biological methylation reactions. Diminished folate status results in chromosome breakage and is associated with several diseases, including colorectal cancer. Folate status is also inversely related to plasma homocys...

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Main Authors: DeVos, Lauren, Chanson, Aurelie, Liu, Zhenhua, Ciappio, Eric D, Parnell, Laurence D, Mason, Joel B, Tucker, Katherine L, Crott, Jimmy W
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728423/
https://ncbi.nlm.nih.gov/pubmed/18842806
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