Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

IpaH proteins are E3 ubiquitin ligases delivered by the type III secretion apparatus into host cells upon infection of humans by the Gram-negative pathogen Shigella flexneri. These proteins comprise a variable leucine-rich repeat—containing N-terminal domain and a conserved C-terminal domain harbori...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Singer, Alexander U, Rohde, John R, Lam, Robert, Skarina, Tatiana, Kagan, Olga, DiLeo, Rosa, Chirgadze, Nickolay Y, Cuff, Marianne E, Joachimiak, Andrzej, Tyers, Mike, Sansonetti, Philippe J, Parsot, Claude, Savchenko, Alexei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764551/
https://ncbi.nlm.nih.gov/pubmed/18997778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1511
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