Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

IpaH proteins are E3 ubiquitin ligases delivered by the type III secretion apparatus into host cells upon infection of humans by the Gram-negative pathogen Shigella flexneri. These proteins comprise a variable leucine-rich repeat—containing N-terminal domain and a conserved C-terminal domain harbori...

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Detalhes bibliográficos
Main Authors: Singer, Alexander U, Rohde, John R, Lam, Robert, Skarina, Tatiana, Kagan, Olga, DiLeo, Rosa, Chirgadze, Nickolay Y, Cuff, Marianne E, Joachimiak, Andrzej, Tyers, Mike, Sansonetti, Philippe J, Parsot, Claude, Savchenko, Alexei
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764551/
https://ncbi.nlm.nih.gov/pubmed/18997778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1511
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