Improvement of RNA secondary structure prediction using RNase H cleavage and randomized oligonucleotides

RNA secondary structure prediction using free energy minimization is one method to gain an approximation of structure. Constraints generated by enzymatic mapping or chemical modification can improve the accuracy of secondary structure prediction. We report a facile method that identifies single-stra...

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Hauptverfasser: Kauffmann, Andrew D., Campagna, Ryan J., Bartels, Chantal B., Childs-Disney, Jessica L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Methods Online
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764423/
https://ncbi.nlm.nih.gov/pubmed/19596816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp587
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