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Inhibition of Escherichia coli RNase P by oligonucleotide directed misfolding of RNA
Oligonucleotide directed misfolding of RNA (ODMiR) uses short oligonucleotides to inhibit RNA function by exploiting the ability of RNA to fold into different structures with similar free energies. It is shown that the 2′-O-methyl oligonucleotide, m(CAGCCUACCCGG), can trap Escherichia coli RNase P R...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370498/ https://ncbi.nlm.nih.gov/pubmed/14624000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5780503 |
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