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The precursor tRNA 3′-CCA interaction with Escherichia coli RNase P RNA is essential for catalysis by RNase P in vivo

The L15 region of Escherichia coli RNase P RNA forms two Watson–Crick base pairs with precursor tRNA 3′-CCA termini (G292-C(75) and G293-C(74)). Here, we analyzed the phenotypes associated with disruption of the G292-C(75) or G293-C(74) pair in vivo. Mutant RNase P RNA alleles (rnpBC292 and rnpBC293...

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Bibliografiske detaljer
Main Authors: Wegscheid, Barbara, Hartmann, Roland K.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664727/
https://ncbi.nlm.nih.gov/pubmed/17135488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.188306
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