Dutch and arctic mutant peptides of β amyloid(1–40) differentially affect the FGF-2 pathway in brain endothelium

Single point mutations of the amyloid precursor protein generate Aβ variants bearing amino acid substitutions at positions 21–23. These mutants are associated with distinct hereditary phenotypes of cerebral amyloid angiopathy, manifesting varying degrees of tropism for brain vessels, and impaired mi...

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Détails bibliographiques
Auteurs principaux: Solito, Raffaella, Corti, Federico, Fossati, Silvia, Mezhericher, Emiliya, Donnini, Sandra, Ghiso, Jorge, Giachetti, Antonio, Rostagno, Agueda, Ziche, Marina
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764262/
https://ncbi.nlm.nih.gov/pubmed/19061884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.11.002
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