Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis

In adult hippocampus, new neurons are continuously generated from neural stem cells (NSCs), but the molecular mechanisms regulating adult neurogenesis remain elusive. We found that Wnt signaling, together with the removal of Sox2, triggered the expression of NeuroD1 in mice. This transcriptional reg...

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Bibliografiske detaljer
Main Authors: Kuwabara, Tomoko, Hsieh, Jenny, Muotri, Alysson, Yeo, Gene, Warashina, Masaki, Lie, Dieter Chichung, Moore, Lynne, Nakashima, Kinichi, Asashima, Makoto, Gage, Fred H
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764260/
https://ncbi.nlm.nih.gov/pubmed/19701198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2360
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