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Staphylococcus aureus Mutant Screen Reveals Interaction of the Human Antimicrobial Peptide Dermcidin with Membrane Phospholipids

Antimicrobial peptides (AMPs) form an important part of the innate host defense. In contrast to most AMPs, human dermcidin has an anionic net charge. To investigate whether bacteria have developed specific mechanisms of resistance to dermcidin, we screened for mutants of the leading human pathogen,...

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Библиографические подробности
Главные авторы: Li, Min, Rigby, Kevin, Lai, Yuping, Nair, Vinod, Peschel, Andreas, Schittek, Birgit, Otto, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764178/
https://ncbi.nlm.nih.gov/pubmed/19596877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00428-09
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