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Staphylococcus aureus Mutant Screen Reveals Interaction of the Human Antimicrobial Peptide Dermcidin with Membrane Phospholipids

Antimicrobial peptides (AMPs) form an important part of the innate host defense. In contrast to most AMPs, human dermcidin has an anionic net charge. To investigate whether bacteria have developed specific mechanisms of resistance to dermcidin, we screened for mutants of the leading human pathogen,...

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Detalhes bibliográficos
Main Authors: Li, Min, Rigby, Kevin, Lai, Yuping, Nair, Vinod, Peschel, Andreas, Schittek, Birgit, Otto, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764178/
https://ncbi.nlm.nih.gov/pubmed/19596877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00428-09
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