Naturally Processed Dermcidin-Derived Peptides Do Not Permeabilize Bacterial Membranes and Kill Microorganisms Irrespective of Their Charge

Dermcidin (DCD) is a recently described antimicrobial peptide, which is constitutively expressed in eccrine sweat glands and transported via sweat to the epidermal surface. By postsecretory proteolytic processing in sweat the dermcidin protein gives rise to several truncated DCD peptides which diffe...

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Main Authors: Steffen, H., Rieg, S., Wiedemann, I., Kalbacher, H., Deeg, M., Sahl, H.-G., Peschel, A., Götz, F., Garbe, C., Schittek, B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2006
Assuntos:
Mechanisms of Action: Physiological Effects
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538671/
https://ncbi.nlm.nih.gov/pubmed/16870749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00181-06
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