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Exploring conformational modes of macromolecular assemblies by multi-particle cryo-EM

Single particle cryo-electron microscopy (cryo-EM) is a technique aimed at structure determination of large macromolecular complexes in their unconstrained, physiological conditions. The power of the method has been demonstrated in selected studies where for highly symmetric molecules the resolution...

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Detalhes bibliográficos
Main Authors: Spahn, Christian M.T., Penczek, Pawel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764000/
https://ncbi.nlm.nih.gov/pubmed/19767196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2009.08.001
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