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Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges
Serious adverse drug reactions (SADRs) are a major cause of morbidity and mortality worldwide. Some SADRs may be predictable, based upon a drug's pharmacodynamic and pharmacokinetic properties. Many, however, appear to be idiosyncratic. Genetic factors may underlie susceptibility to SADRs and t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763923/ https://ncbi.nlm.nih.gov/pubmed/17971785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2423 |
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