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Accelerating phage-display library selection by reversible and site-specific biotinylation

Immobilization of a target molecule to a solid support is an indispensable step in phage display library sorting. Here we describe an immobilization method that addresses shortcomings of existing strategies. Our method is based on the use of a polyhistidine-tagged (His-tagged) target molecule and (B...

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Detaylı Bibliyografya
Asıl Yazarlar: Koide, Akiko, Wojcik, John, Gilbreth, Ryan N., Reichel, Annett, Piehler, Jacob, Koide, Shohei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763796/
https://ncbi.nlm.nih.gov/pubmed/19737805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzp053
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