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Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance
A majority of subjects with insulin resistance and hyperinsulinemia can maintain their blood glucose levels normal for the whole life presumably through protein kinase B (Akt)-dependent insulin signaling. In this study, we found that the basal Akt phosphorylation level was increased in liver and gas...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763787/ https://ncbi.nlm.nih.gov/pubmed/19638508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00374.2009 |
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