Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia: INHIBITION OF FoxO1-DEPENDENT EXPRESSION OF KEY AUTOPHAGY GENES BY INSULIN

Autophagy is essential for maintaining both survival and health of cells. Autophagy is normally suppressed by amino acids and insulin. It is unclear what happens to the autophagy activity in the presence of insulin resistance and hyperinsulinemia. In this study, we examined the autophagy activity in...

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Bibliografiske detaljer
Main Authors: Liu, Hui-Yu, Han, Jianmin, Cao, Sophia Y., Hong, Tao, Zhuo, Degen, Shi, Jianbo, Liu, Zhenqi, Cao, Wenhong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Metabolism and Bioenergetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781544/
https://ncbi.nlm.nih.gov/pubmed/19758991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033936
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