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Suppression of Hepatic Glucose Production by Human Neutrophil α-Defensins through a Signaling Pathway Distinct from Insulin

In this study, we tested the hypothesis that human neutrophil α-defensins (HNPs) inhibit hepatic glucose production through a signaling pathway distinct from insulin. The effect of HNP-1 on fasting blood glucose levels and the expression of hepatic gluconeogenic genes was first examined. Using hyper...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Hui-Yu, Collins, Qu Fan, Moukdar, Fatiha, Zhuo, Degen, Han, Jianmin, Hong, Tao, Collins, Sheila, Cao, Wenhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335365/
https://ncbi.nlm.nih.gov/pubmed/18347011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801033200
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