Interleukin-7 Receptor Signaling Network: An Integrated Systems Perspective

Interleukin-7 (IL-7) is an essential cytokine for the development and homeostatic maintenance of T and B lymphocytes. Binding of IL-7 to its cognate receptor, the IL-7 receptor (IL-7R), activates multiple pathways that regulate lymphocyte survival, glucose uptake, proliferation and differentiation....

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Detalhes bibliográficos
Main Authors: Palmer, Megan J, Mahajan, Vinay S, Trajman, Lily C, Irvine, Darrell J, Lauffenburger, Douglas A, Chen, Jianzhu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763551/
https://ncbi.nlm.nih.gov/pubmed/18445337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2008.10
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