The Role of P-glycoprotein in Cerebral Amyloid Angiopathy; Implications for the Early Pathogenesis of Alzheimer’s Disease

It has been shown in vitro that β-amyloid (Aβ) is transported by P-glycoprotein (P-gp). Previously, we demonstrated that Aβ immunoreactivity is significantly elevated in brain tissue of individuals with low expression of P-gp in vascular endothelial cells. These findings led us to hypothesize that P...

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Main Authors: Vogelgesang, Silke, Warzok, Rolf W., Cascorbi, Ingolf, Kunert-Keil, Christiane, Schroeder, Eike, Kroemer, Heyo K., Siegmund, Werner, Walker, Lary C., Pahnke, Jens
Format: Artigo
Jezik:Inglês
Izdano: 2004
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763541/
https://ncbi.nlm.nih.gov/pubmed/15975076
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