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Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching

BACKGROUND: TDP-43 is an evolutionarily conserved RNA-binding protein implicated in the pathogenesis of frontotemporal dementia (FTD), sporadic and familial amyotrophic lateral sclerosis (ALS), and possibly other neurodegenerative diseases. In diseased neurons, TDP-43 is depleted in the nucleus, sug...

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Autori principali: Lu, Yubing, Ferris, Jacob, Gao, Fen-Biao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762964/
https://ncbi.nlm.nih.gov/pubmed/19781077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-2-30
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