Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL

Resequencing genes provides the opportunity to assess the full spectrum of variants that influence complex traits. Here we report the first application of resequencing to a large population (n = 3,551) to examine the role of the adipokine ANGPTL4 in lipid metabolism. Nonsynonymous variants in ANGPTL...

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Bibliografiske detaljer
Main Authors: Romeo, Stefano, Pennacchio, Len A, Fu, Yunxin, Boerwinkle, Eric, Tybjaerg-Hansen, Anne, Hobbs, Helen H, Cohen, Jonathan C
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762948/
https://ncbi.nlm.nih.gov/pubmed/17322881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1984
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