Thymidine Kinase 1 and Thymidine Phosphorylase Expression in Non–Small-cell Lung Carcinoma in Relation to Angiogenesis and Proliferation

The thymidine salvage pathway enzymes thymidine kinase 1 (TK1) and thymidine phosphorylase (TP) compete for thymidine as a substrate and catalyze opposing synthetic and catabolic reactions that have been implicated in the control of proliferation and angiogenesis, respectively. We investigated the r...

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Autori principali: Brockenbrough, J. Scott, Morihara, Janice K., Hawes, Stephen E., Stern, Joshua E., Rasey, Janet S., Wiens, Linda W., Feng, Qinghua, Vesselle, Hubert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Histochemical Society 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762886/
https://ncbi.nlm.nih.gov/pubmed/19654105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.2009.952804
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