Impact of thymidine phosphorylase surexpression on fluoropyrimidine activity and on tumour angiogenesis

Tumoral thymidine phosphorylase (TP) appears to play a dual role by being involved in neoangiogenesis and by activating 5FU prodrugs at the tumoral target site. The aim of the study was to investigate more thoroughly these potential physiological and pharmacological roles of TP. A rat carcinoma cell...

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Detalles Bibliográficos
Autores principales: Marchetti, S, Chazal, M, Dubreuil, A, Fischel, J L, Etienne, M C, Milano, G
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2001
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364074/
https://ncbi.nlm.nih.gov/pubmed/11487278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1908
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