Impact of thymidine phosphorylase surexpression on fluoropyrimidine activity and on tumour angiogenesis

Tumoral thymidine phosphorylase (TP) appears to play a dual role by being involved in neoangiogenesis and by activating 5FU prodrugs at the tumoral target site. The aim of the study was to investigate more thoroughly these potential physiological and pharmacological roles of TP. A rat carcinoma cell...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Marchetti, S, Chazal, M, Dubreuil, A, Fischel, J L, Etienne, M C, Milano, G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2001
Konular:
Regular Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364074/
https://ncbi.nlm.nih.gov/pubmed/11487278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1908
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