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Glucocorticoids can activate the α-ENaC gene promoter independently of SGK1

The role of SGK1 (serum- and glucocorticoid-induced protein kinase 1) in the glucocorticoid induction of α-ENaC (epithelial Na(+) channel α subunit) gene transcription was explored by monitoring the transcriptional activity of a luciferase-linked, α-ENaC reporter gene construct (pGL3-KR1) expressed...

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Autors principals: McTavish, Niall, Getty, Jennet, Burchell, Ann, Wilson, Stuart M.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762689/
https://ncbi.nlm.nih.gov/pubmed/19619128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090366
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