E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1

Metastasis-associated protein 1 (MTA1), a component of the nucleosome remodeling and histone deacetylation (NuRD) complex, is widely upregulated in human cancers. However, the mechanism for regulating its protein stability remains unknown. Here we report that MTA1 is an ubiquitinated protein and tar...

Full description

Saved in:
Bibliographic Details
Main Authors: Li, Da-Qiang, Ohshiro, Kazufumi, Reddy, Sirigiri Divijendra Natha, Pakala, Suresh B., Lee, Mong-Hong, Zhang, Yanping, Rayala, Suresh K., Kumar, Rakesh
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762678/
https://ncbi.nlm.nih.gov/pubmed/19805145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908027106
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items