Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition

The strength of synaptic inhibition depends partly on the number of GABA(A) receptors (GABA(A)Rs) found at synaptic sites. The trafficking of GABA(A)Rs within the endocytic pathway is a key determinant of surface GABA(A)R number and is altered in neuropathologies, such as cerebral ischemia. However,...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Arancibia-Cárcamo, I. Lorena, Yuen, Eunice Y., Muir, James, Lumb, Michael J., Michels, Guido, Saliba, Richard S., Smart, Trevor G., Yan, Zhen, Kittler, Josef T., Moss, Stephen J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762659/
https://ncbi.nlm.nih.gov/pubmed/19815531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905502106
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk