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Prion proteins with pathogenic and protective mutations show similar structure and dynamics
Conformational change in the prion protein (PrP) is thought to be responsible for a group of rare but fatal neurodegenerative diseases of humans and other animals, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. However, little is known about the mechanism by which normal c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762478/ https://ncbi.nlm.nih.gov/pubmed/19618915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900923b |
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