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Growth suppression by ursodeoxycholic acid involves caveolin-1 enhanced degradation of EGFR
Ursodeoxycholic acid (UDCA) has been shown to prevent colon tumorigenesis in animal models and in humans. In vitro work indicates that this bile acid can suppress cell growth and mitogenic signaling suggesting that UDCA may be an anti-proliferative agent. However, the mechanism by which UDCA functio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762387/ https://ncbi.nlm.nih.gov/pubmed/19446582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2009.05.003 |
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