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TNFα induces HIF-1α expression through activation of IKKβ
The transcription factor hypoxia-inducible factor 1α (HIF-1α) is regulated by oxygen availability as well as various inflammatory mediators, including tumor necrosis factor α (TNFα). Early work suggested that the phosphatidylinositol-3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) signal...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2762003/ https://ncbi.nlm.nih.gov/pubmed/19766100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.09.042 |
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