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Inhibition of the ubiquitin-proteasome system in Alzheimer's disease

Alzheimer's disease is the most common cause of dementia in the elderly. Although several genetic defects have been identified in patients with a family history of this disease, the majority of cases involve individuals with no known genetic predisposition. A mutant form of ubiquitin, termed Ub...

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Autors principals: Lam, Y. Amy, Pickart, Cecile M., Alban, Andrew, Landon, Michael, Jamieson, Craig, Ramage, Robert, Mayer, R. John, Layfield, Robert
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC27620/
https://ncbi.nlm.nih.gov/pubmed/10944193
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