Inhibition of the ubiquitin-proteasome system in Alzheimer's disease

Alzheimer's disease is the most common cause of dementia in the elderly. Although several genetic defects have been identified in patients with a family history of this disease, the majority of cases involve individuals with no known genetic predisposition. A mutant form of ubiquitin, termed Ub(+1),...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Lam, Y. Amy, Pickart, Cecile M., Alban, Andrew, Landon, Michael, Jamieson, Craig, Ramage, Robert, Mayer, R. John, Layfield, Robert
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2000
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10944193/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.170173897
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