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α-Tocopheryl Succinate as a Scaffold to Develop Potent Inhibitors of Breast Cancer Cell Adhesion

This study is aimed at the pharmacological exploitation of α-tocopheryl succinate (1) to develop potent anti-adhesion agents. Considering the structural cooperativity between the phytyl chain and the carboxylic terminus in determining the anti-adhesion activity, our structural optimization led to co...

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Detalhes bibliográficos
Main Authors: Wang, Dasheng, Chuang, Hsiao-Ching, Weng, Shu-Chuan, Huang, Po-Hsien, Hsieh, Hao-Yu, Kulp, Samuel K., Chen, Ching-Shih
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761948/
https://ncbi.nlm.nih.gov/pubmed/19708661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9002457
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