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The interaction of Arp2/3 complex with actin: Nucleation, high affinity pointed end capping, and formation of branching networks of filaments

The Arp2/3 complex is a stable assembly of seven protein subunits including two actin-related proteins (Arp2 and Arp3) and five novel proteins. Previous work showed that this complex binds to the sides of actin filaments and is concentrated at the leading edges of motile cells. Here, we show that Ar...

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Bibliographic Details
Main Authors: Mullins, R. Dyche, Heuser, John A., Pollard, Thomas D.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC27619/
https://ncbi.nlm.nih.gov/pubmed/9600938
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