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Detection of gene loops by 3C in yeast

“Chromosome conformation capture” (3C) is a powerful method to detect physical interaction between any two genomic loci. 3C involves formaldehyde crosslinking to stabilize transient interactions, followed by restriction digestion, ligation and locus-specific PCR. Accordingly, 3C reveals complex thre...

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Hlavní autoři: Singh, Badri Nath, Ansari, Athar, Hampsey, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761752/
https://ncbi.nlm.nih.gov/pubmed/19269325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.02.018
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