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Detection of gene loops by 3C in yeast
“Chromosome conformation capture” (3C) is a powerful method to detect physical interaction between any two genomic loci. 3C involves formaldehyde crosslinking to stabilize transient interactions, followed by restriction digestion, ligation and locus-specific PCR. Accordingly, 3C reveals complex thre...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761752/ https://ncbi.nlm.nih.gov/pubmed/19269325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.02.018 |
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