A physiological role for gene loops in yeast

DNA loops that juxtapose the promoter and terminator regions of RNA polymerase II-transcribed genes have been identified in yeast and mammalian cells. Loop formation is transcription-dependent and requires components of the pre-mRNA 3′-end processing machinery. Here we report that looping at the yea...

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Bibliographic Details
Main Authors: Lainé, Jean-Philippe, Singh, Badri Nath, Krishnamurthy, Shankarling, Hampsey, Michael
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2009
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779762/
https://ncbi.nlm.nih.gov/pubmed/19933150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1823609
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