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Characterization of mutant MUTYH proteins associated with familial colorectal cancer
BACKGROUND & AIMS: The human mutyh gene encodes a base excision repair (BER) protein that prevents G:C to T:A transversions in DNA. Biallelic mutations in this gene are associated with recessively inherited familial colorectal cancer. The aim of this study was to characterize the functional acti...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761659/ https://ncbi.nlm.nih.gov/pubmed/18534194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.04.035 |
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