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Interaction of Human DNA Polymerase α and DNA Polymerase I from Bacillus stearothermophilus with Hypoxanthine and 8-Oxoguanine Nucleotides

To better understand how DNA polymerases interact with mutagenic bases, we examined how human DNA polymerase α (pol α), a B family enzyme, and DNA polymerase from Bacillus stearothermophilus (BF), an A family enzyme, generate adenine:hypoxanthine and adenine:8-oxo-7,8-dihydroguanine (8-oxoG) base pa...

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Bibliografische gegevens
Hoofdauteurs: Patro, Jennifer N., Urban, Milan, Kuchta, Robert D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761430/
https://ncbi.nlm.nih.gov/pubmed/19642651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900777s
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