Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin

Controversy remains over whether the cancer stem cell (CSC) theory applies to all tumors. To determine whether cells within a highly aggressive solid tumor are stochastically or hierarchically organized, we combined a reporter system where the nucleostemin (NS) promoter drives GFP expression (termed...

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Detalhes bibliográficos
Main Authors: Tamase, Akira, Muraguchi, Teruyuki, Naka, Kazuhito, Tanaka, Shingo, Kinoshita, Masashi, Hoshii, Takayuki, Ohmura, Masako, Shugo, Haruhiko, Ooshio, Takako, Nakada, Mitsutoshi, Sawamoto, Kazunobu, Onodera, Masafumi, Matsumoto, Kunio, Oshima, Masanobu, Asano, Masahide, Saya, Hideyuki, Okano, Hideyuki, Suda, Toshio, Hamada, Jun-ichiro, Hirao, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761321/
https://ncbi.nlm.nih.gov/pubmed/19805150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905016106
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