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Repair of gaps opposite lesions by homologous recombination in mammalian cells
Damages in the DNA template inhibit the progression of replication, which may cause single-stranded gaps. Such situations can be tolerated by translesion DNA synthesis (TLS), or by homology-dependent repair (HDR), which is based on transfer or copying of the missing information from the replicated s...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2009
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761288/ https://ncbi.nlm.nih.gov/pubmed/19654238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp632 |
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