A wave of nascent transcription on activated human genes

Genome-wide studies reveal that transcription by RNA polymerase II (Pol II) is dynamically regulated. To obtain a comprehensive view of a single transcription cycle, we switched on transcription of five long human genes (>100 kbp) with tumor necrosis factor-α (TNFα) and monitored (using microarra...

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Hauptverfasser: Wada, Youichiro, Ohta, Yoshihiro, Xu, Meng, Tsutsumi, Shuichi, Minami, Takashi, Inoue, Kenji, Komura, Daisuke, Kitakami, Jun'ichi, Oshida, Nobuhiko, Papantonis, Argyris, Izumi, Akashi, Kobayashi, Mika, Meguro, Hiroko, Kanki, Yasuharu, Mimura, Imari, Yamamoto, Kazuki, Mataki, Chikage, Hamakubo, Takao, Shirahige, Katsuhiko, Aburatani, Hiroyuki, Kimura, Hiroshi, Kodama, Tatsuhiko, Cook, Peter R., Ihara, Sigeo
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761237/
https://ncbi.nlm.nih.gov/pubmed/19826084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902573106
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