Dynamic Change of Chromatin Conformation in Response to Hypoxia Enhances the Expression of GLUT3 (SLC2A3) by Cooperative Interaction of Hypoxia-Inducible Factor 1 and KDM3A

Hypoxia-inducible factor 1 (HIF1) is a master regulator of adaptive gene expression under hypoxia. However, a role for HIF1 in the epigenetic regulation remains unknown. Genome-wide analysis of HIF1 binding sites (chromatin immunoprecipitation [ChIP] with deep sequencing) of endothelial cells clarif...

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Main Authors: Mimura, Imari, Nangaku, Masaomi, Kanki, Yasuharu, Tsutsumi, Shuichi, Inoue, Tsuyoshi, Kohro, Takahide, Yamamoto, Shogo, Fujita, Takanori, Shimamura, Teppei, Suehiro, Jun-ichi, Taguchi, Akashi, Kobayashi, Mika, Tanimura, Kyoko, Inagaki, Takeshi, Tanaka, Toshiya, Hamakubo, Takao, Sakai, Juro, Aburatani, Hiroyuki, Kodama, Tatsuhiko, Wada, Youichiro
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434521/
https://ncbi.nlm.nih.gov/pubmed/22645302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06643-11
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