Gene medicine for cancer treatment: Commercially available medicine and accumulated clinical data in China

Loss of p53 function compromises genetic homeostasis, which induces deregulated DNA replication, damages DNA, and subsequently results in increased resistance to anticancer agents. Pharmacological approaches using recombinant adenoviruses (Ad) have been developed to restore the p53 functions. Anothe...

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Main Authors: Ma, Guangyu, Shimada, Hideaki, Hiroshima, Kenzo, Tada, Yuji, Suzuki, Nobuo, Tagawa, Masatoshi
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2009
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761194/
https://ncbi.nlm.nih.gov/pubmed/19920899
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